In Vivo Scientist Job at Garuda Therapeutics, Cambridge, MA

YWpsbHRHTm1Rc1ZVWkNXUGQ3VDcyd2wy
  • Garuda Therapeutics
  • Cambridge, MA

Job Description

The successful candidate will have outstanding expertise in mouse handling and mouse procedures. They will be responsible for managing mouse colonies, performing project-specific in vivo experiments, intravenous injections of hematopoietic stem cells in humanized murine models, retro-orbital and submandibular blood collection, and blood cell FACS analyses and in vivo imaging. This is a collaborative role that will be partnering with other team members to assist with project-specific- in vivo experiments as well as other needs across the process development function.

Role and Responsibilities:

  • Hands-on role with a commitment to designing, conducting and analyzing in vivo studies to assess engraftment of hematopoietic stem cells
  • Execute pluripotent stem cell culture and differentiation into hematopoietic stem cells to support process development, optimization, and characterization
  • Document experimental procedures and results according to established guidelines; Perform statistical analysis of experimental data
  • Collaborate effectively within departmental teams, engage in team discussions to resolve issues, and lead projects with a fully integrated team to facilitate successful outcomes
  • Prior experience in bioreactor-based process development for iPSC-derived cell therapies is highly desirable

Qualifications:

  • Advanced degree (M.S. or Ph.D.) in molecular biology or pharmacology, with at least 2 years of industry experience is required
  • Experience working with human induced pluripotent stem cells (iPSC), hematopoietic stem cells (HSC), and/or immune cell biology; including scale-up processes utilizing bioreactors such as PBS vertical wheel, Rotea counterflow centrifuge is required
  • Proficiency with in-vivo techniques including animal handling, intra-bone and intravenous transplants, blood collection and tissue dissection
  • Experience in standard processing techniques including flow cytometry, molecular biology assays such as CFUs, immunological assays, and aseptic cell culture technique is required
  • Experience with experiment design tools such as FlowJo and practical knowledge of statistical analysis is required
  • Strong organizational, analytical, problem-solving, root-cause-analysis, and trouble-shooting skills are required

Job Tags

Similar Jobs

J-Pack Logistics Inc.

FedEx Delivery Driver Job at J-Pack Logistics Inc.

 ...FedEx Delivery Driver Needed Join Our Team! J-Pack Logistics Inc., an independent service provider for FedEx Ground, is excited to announce immediate openings for Delivery Drivers in the New Hill, NC area. We're looking for dependable, motivated individuals to join our... 

Adfero

Director of Digital Media Job at Adfero

 ...Adfero is seeking a full-time Director of Digital and Paid Media with experience and deep interest in digital communications strategies to join our company. Were looking for someone to elevate our paid media strategies across all practices and stay on the leading edge... 

University of Kansas

Morning News Host/Reporter | University of Kansas Job at University of Kansas

 ...Position Overview The Morning Edition Host/Reporter delivers the local segments of "Morning Edition," National Public Radio's weekday news magazine on Kansas Public Radio (hereafter "KPR"), licensed by the University of Kansas in Lawrence. This person gathers, edits... 

ROCS Grad Staffing

Operations Coordinator Job at ROCS Grad Staffing

 ...Work Here: This is a great opportunity for an administrative professional with some coordination experience to join an international company and be able to step into a rigorous role that assists with contract and audit coordination. Responsibilities: Assist with... 

The H&K Group

Construction Party Chief Job at The H&K Group

 ...department will provide you with the latest technology the Survey industry has to offer including; 3D Machine Control, Data acquisition via drone and scanners, Survey and modeling software, Robotic and GNSS hardware. The H&K survey department exclusively leverages Trimble...