Job Title: Scientist II
Description: We are seeking a highly skilled and motivated scientist at the Scientist II level to join our Immunology and Respiratory Disease Department located in Ridgefield CT. The successful candidate with a demonstrated ability to work in a matrix environment will work within the Translational Biology group to develop in vitro cellular models relevant to fibrotic diseases. Candidate will work in a highly collaborative group and will support research projects that aim deliver innovative drug concepts for clinical development.
Duties & Responsibilities:
Work with lab managers and team members to plan and execute cellular assays using primary human cells. Experience with 2D and 3D cultures is a plus.
Execute relevant cellular/molecule functional assays (ELISA TaqMan qPCR colormetric based assays etc.) and cellbased imaging with minimal supervision.
Perform literature searches and extract relevant information from published protocols and implements them; demonstrate the ability to interpret outcome of experiments and to propose appropriate followup.
Effectively communicate work orally and in writing; independently complete high quality work notebook and contribute to writing protocols and provide input for scientific reports; demonstrate agility in learning new techniques and adaptability to a matrixed work culture.
Work in a collaborative manner with other members in the department; participate in cross departmental project teams when needed.
Report and treat data with a high level of integrity and ethics; comply with applicable regulations perform all work in a safe manner; maintain proper records in accordance with SOPs and policies.
Skills:
Previous handson experience in tissue culture is a must (primary human cell culture experience is a plus).
Practical experience in basic molecular assays such as RNA isolation qPCR and/or ELISA is preferred.
Practical experience or knowledge in imaging based cellular assay (i.e. immunofluorescence livecell imaging) is a plus.
Proficient with basic analysis software such as Excel (must) and GraphPad Prism (preferred).
Strong ability to work in a matrix environment.
Requirements:
Bachelors Degree with 3 years experience or Masters Degree in immunology molecular biology biochemistry or equivalent experience in related field.
DNA/RNA PURIFICATION
CELLULAR
IMMUNOLOGY
TISSUE CULTURE
CELL CULTURE
Additional Skills:
SOPS
BIOCHEMISTRY
WRITING PROTOCOLS
ELISA
EXCEL
ADME
IMAGING
QPCR
Location:
Ridgefield CT
900 RIDGEBURY RD BLDG RD
Schedule:
Start Date: 02/01/2025
Estimated End Date: 01/31/2027
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